TGFbeta1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TGFbeta1 |
| Clone | [4C1-8C8-1E7] |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Stimulates sustained production of collagen through the activation of CREB3L1 by regulated intramembrane proteolysis (RIP) (PubMed:25310401). Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated |
| Immunogen | Immunogen: Synthetic peptide conjugated to KLH. |
| Other Names | [TGF beta 1; TGFB; CED; LAP; TGFB1] |
| Gene, Accession # | [TGFbeta1], Gene ID: 7040, NCBI: NP_000651.3, UniProt: P01137 |
| Catalog # | MBS8539738 |
| Price | $280 |
| Order / More Info | TGFbeta1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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