GDNF - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGDNF - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Homozygous knockout mice
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of mouse GDNF
Other Names[glial cell line-derived neurotrophic factor isoform 2; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; glial cell line derived neurotrophic factor; Astrocyte-derived trophic factor; ATF]
Gene, Accession #[GDNF], Gene ID: 14573, NCBI: NP_001288261.1, UniProt: P48540
Catalog #MBS3223551
Price$335
Order / More InfoGDNF - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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