Edit |   |
---|---|
Antigenic Specificity | CD74 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry, Immunoblot, Immunocytochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD74 [Mouse monoclonal antibody recognizes human CD74.]. This antibody recognizes human CD74. CD74 is a non-polymorphic type II integral membrane protein. It has a short N-terminal cytoplasmic tail of 28 amino acids followed by a single 24-aa transmembrane region and an approximately 150-aa lumenal domain. CD74 functions mainly as an MHC class II chaperone which promotes ER exit of MHC class II molecules by directing them to endocytic compartments, preventing peptide binding in the ER, and contributing to peptide editing in the MHC class II compartment. CD74 has recently been shown to have a role as an accessory signaling molecule because of its high-affinity binding to the pro-inflammatory cytokine macrophage migration inhib |
Immunogen | Antigen: Synthetic peptide corresponding to the human CD74 invariant chain (aa 12-28) conjugated to KLH. |
Other Names | [CD74], [CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG] |
Gene, Accession # | Gene ID: 972, UniProt: P04233 |
Catalog # | MBS190488 |
Price | $355 |
Order / More Info | CD74 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |