MMP2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMMP2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (
ImmunogenImmunogen: Fusion protein of human MMP2
Other Names[MMP2; MMP2; CLG4; CLG4A; MMP-II; MONA; TBE-1;], [MMP2; MMP2; CLG4; MONA; CLG4A; TBE-1; MMP-II; CLG4A; MMP-2]
Gene, Accession #Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253
Catalog #MBS125214
Price$200, $275, $430
Order / More InfoMMP2 Antibody from MYBIOSOURCE INC.
Product Specific References1. McCawley, L.J. and Matrisian, L.M. (2001) Curr. Opin. Cell Biol. 13, 534-540. 2. Coussens, L.M. et al. (2002) Science 295, 2387-2391. 3. Sternlicht, M.D. et al. (1999) Cell 98, 137-146. 4. Vu, T.H. et al. (1998) Cell 93, 411-422. 5. Nagase, H. et al. (1990) Biochemistry 29, 5783-5789.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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