AP2M1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | AP2M1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: AP2M1 Antibody detects endogenous levels of total AP2M1. The AP-2 coat assembly protein complex is an important component of clathrin-coated pits involved in receptor-mediated endocytosis at the plasma membrane (1-3). Each AP-2 heterotetramer is composed of alpha, beta, mu, and sigma protein subunits. The 50 kDa mu subunit (AP-2mu, AP2M1) is located at the core of the AP-2 complex and mediates interaction between the cargo protein and the clathrin-coated pit (1-4). The carboxy-terminal AP2M1 region recognizes the tyrosine-based, endocytotic sorting motif YXX phi found in cargo proteins and helps to bring the cargo protein to the clathrin-coated pit. Non-canonical, tyrosine-based endocytotic sorting signals can also promote inte |
| Immunogen | Immunogen: Recombinant protein of human AP2M1 |
| Other Names | [AP50; CLAPM1; mu2] |
| Gene, Accession # | [AP2M1], Gene ID: 1173, NCBI: NP_001020376.1, UniProt: Q96CW1 |
| Catalog # | MBS8516431 |
| Price | $290 |
| Order / More Info | AP2M1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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