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Antigenic Specificity | CIB1 |
Clone | [5A1F5E12; 5A1H7E12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R. |
Immunogen | Immunogen: Purified recombinant fragment of CIB1 expressed in E. Coli. |
Other Names | [CIB; KIP; KIP1; SIP2-28] |
Gene, Accession # | [CIB1], Gene ID: 10519, NCBI: Q99828.4, UniProt: Q99828 |
Catalog # | MBS8538317 |
Price | $280 |
Order / More Info | CIB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |