Human Histone-lysine N-methyltransferase SUV39H2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Histone-lysine N-methyltransferase SUV39H2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionHistone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May
ImmunogenImmunogen: Recombinant human Histone-lysine N-methyltransferase SUV39H2 protein(201-410aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54340 / sc-54342 / sc-54340 / sc-54342 / sc-130886
Other Names[Histone H3-K9 methyltransferase 2; H3-K9-HMTase 2; Lysine N-methyltransferase 1B; Suppressor of variegation 3-9 homolog 2; Su(var)3-9 homolog 2; SUV39H2; KMT1B], [SUV39H2; SUV39H2; KMT1B; KMT1B; H3-K9-HMTase 2; Su(var)3-9 homolog 2]
Gene, Accession #[SUV39H2], Gene ID: 79723, NCBI: NP_001180353.1, UniProt: Q9H5I1
Catalog #MBS1496509
Price$120, $160
Order / More InfoHuman Histone-lysine N-methyltransferase SUV39H2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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