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Antigenic Specificity | SP-100 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SP-100 Polyclonal Antibody detects endogenous levels of SP-100 protein. SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one of which encodes a high-mobility group protein. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human SP-100 at AA range: 250-330 |
Other Names | [Rabbit SP-100; SP100; Nuclear autoantigen Sp-100; Lysp100b; Nuclear dot-associated Sp100 protein; Speckled 100 kDa] |
Gene, Accession # | [SP-100], Gene ID: 6672, NCBI: NP_001073860.1, UniProt: P23497 |
Catalog # | MBS9706885 |
Price | $130, $220, $325 |
Order / More Info | SP-100 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |