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Antigenic Specificity | Human Tyrosine-protein kinase JAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they ar |
Immunogen | Immunogen: Recombinant human Tyrosine-protein kinase JAK2 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34479 / sc-34480 / sc-278 / sc-294 / sc-7229 |
Other Names | [Janus kinase 2; JAK2], [JAK2; JAK2; JTK10; THCYT3; JAK-2] |
Gene, Accession # | [JAK2], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674 |
Catalog # | MBS1489450 |
Price | $160, $235 |
Order / More Info | Human Tyrosine-protein kinase JAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |