Bcl-xL (Phospho-Ser62) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bcl-xL (Phospho-Ser62) |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunoblotting (IB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous human, mouse, and rat Bcl-xL only when phosphorylated at serine 62. B-cell lymphoma-extra large (Bcl-xl, or BCL2-like 1 isoform 1) is a transmembrane protein in the mitochondria. It is a member of the Bcl-2 family of proteins and acts as a pro-survival protein by preventing the release of mitochondrial cytochrome c, which would lead to caspase activation. Relative amounts of pro- and anti-survival Bcl-2 family proteins define whether a cell will undergo cell death: if more Bcl-xL is present, then pores are non-permeable to pro-apoptotic molecules and the cell survives. |
| Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 62 derived from human Bcl-xL and conjugated to KLH. |
| Other Names | [bcl-2-like protein 1 isoform Bcl-X(L); Bcl-2-like protein 1; bcl-2-like protein 1; BCL2 like 1; Apoptosis regulator Bcl-X], [BCL2L1; BCL2L1; BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S; BCL2L; BCLX; Bcl2-L-1] |
| Gene, Accession # | [Bcl-xL], Gene ID: 598, NCBI: NP_612815.1, UniProt: Q07817 |
| Catalog # | MBS191077 |
| Price | $340 |
| Order / More Info | Bcl-xL (Phospho-Ser62) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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