MALT1 (MALT-Lymphoma Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MALT1 (MALT-Lymphoma Marker) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and p |
| Immunogen | Immunogen: Recombinant fragment (around aa701-808) of human MALT1 protein (exact sequence is proprietary) |
| Other Names | [Caspase-like protein; MALT lymphoma-associated translocation; MLT1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase] |
| Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: NP_006776.1, UniProt: Q9UDY8 |
| Catalog # | MBS4380790 |
| Price | $190, $340, $340 |
| Order / More Info | MALT1 (MALT-Lymphoma Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ye H., et. al. J Pathol 2005; 205: 293 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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