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Antigenic Specificity | Cystatin B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Cystatin B. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations i |
Immunogen | Immunogen: Synthesized peptide derived from part region of human Cystatin B protein at amino acid sequence of 20-60 |
Other Names | [Rabbit Cystatin B; Cystatin-B; CPI-B; Liver thiol proteinase inhibitor; Stefin-B] |
Gene, Accession # | [CSTB], Gene ID: 1476, NCBI: NP_000091.1, UniProt: P04080 |
Catalog # | MBS9708903 |
Price | $130, $220, $325 |
Order / More Info | Cystatin B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |