Myosin IIa Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Myosin IIa antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Myosin IIa |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Nonmuscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity. The holoenzyme consists of two identical heavy chains and two sets of light chains. The light chains (MLCs) regulate myosin II activity and stability. The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10, and MYH14, which generate three different nonmuscle myosin II isoforms, IIa, IIb, and IIc, respectively (reviewed in 1). While all three isoforms perform the same enzymatic tasks, binding to and contracting actin filaments coupled to ATP hydrolysis, their cellular functions do not appear to be redundant and they have different subcellular distributions (2-5). The carboxy-terminal tail domain of myosin I |
| Immunogen | Immunogen: Fusion protein of human MYH9 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [MYH9; DFNA17; EPSTS; FTNS; MGC104539; MHA; NMMHCA; Myosin Iia] |
| Gene, Accession # | [NMHC-II-A], Gene ID: 4627, NCBI: NP_002464.1, UniProt: P35579 |
| Catalog # | MBS8500880 |
| Price | $310 |
| Order / More Info | Myosin IIa Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Conti, M.A. and Adelstein, R.S. (2008) J Cell Sci 121, 11-18. 2. Sandquist, J.C. et al. (2006) J Biol Chem 281, 35873-83. 3. Even-Ram, S. et al. (2007) Nat Cell Biol 9, 299-309. 4. Vicente-Manzanares, M. et al. (2007) J Cell Biol 176, 573-80. 5. Wylie, S.R. and Chantler, P.D. (2008) Mol Biol Cell 19, 3956-68. 6. Sandquist, J.C. and Means, A.R. (2008) Mol Biol Cell 19, 5156-67. 7. Dulyaninova, N.G. et al. (2007) Mol Biol Cell 18, 3144-55. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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