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Antigenic Specificity | FOXA1/HNF3A |
Clone | [FOXA1/1516] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors.HNF-1 (), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity |
Immunogen | Immunogen: Recombinant human FOXA1 protein fragment (aa372-472) (exact sequence is proprietary) |
Other Names | [Forkhead box protein A1 (FOXA1); Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A); Transcription factor 3A (TCF-3A or TCF3A)] |
Gene, Accession # | [FOXA1], Gene ID: 3169, NCBI: NP_004487, UniProt: P55317 |
Catalog # | MBS4380983 |
Price | $190, $340, $340 |
Order / More Info | FOXA1/HNF3A Antibody from MYBIOSOURCE INC. |
Product Specific References | Andre Albergaria, et al. Breast Cancer Research 2009, 11:R40. |