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Antigenic Specificity | TPPP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TPPP antibody detects endogenous levels of total TPPP. Function: May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.Subunit Structure: Homodimer. Binds tubulin; binding is inhibited by GTP (By similarity). Interacts with GSK3 (By similarity). Interacts with MAPK1 (By similarity). Interacts with GAPDH; the interaction is direct (By similarity). Interacts with LIMK1 (via the PDZ domain); the interaction is direct.Post-translational Modifications: Poor substrate for GSK3 (By similarity). Phosphorylated by L |
Immunogen | Immunogen: A synthesized peptide derived from human TPPP Subcellular Location: Cytoplasm. Cytoplasm, Cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies. Tissue Specificity: Widely expressed. |
Other Names | [25 kDa brain specific protein; 25 kDa brain-specific protein; Brain specific protein p25 alpha; Glycogen synthase kinase 3 (GSK3) inhibitor p24; OTTHUMP00000161630; p24; p25; p25-alpha; p25alpha; TPPP; TPPP/p25; TPPP_HUMAN; TPPP1; Tubulin polymerization promoting protein; Tubulin polymerization-promoting protein] |
Gene, Accession # | [TPPP], Gene ID: 11076, NCBI: NP_008961.1, UniProt: O94811 |
Catalog # | MBS9608416 |
Price | $240, $280 |
Order / More Info | TPPP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |