CD154, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD154, Human |
| Clone | 24-31 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytomery(FC/FACS), FS, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 24-31 recognizes human CD40 ligand (CD40L), also referred as CD154. CD40L is a transmembrane cell surface glycoprotein of 39 kDa expressed mainly on CD4 T cells and platelets in an activation-dependent manner. The interaction of CD40L on activated CD4 T cells with CD40 on antigen presenting cells is essential for the T-cell-dependent humoral immune respons. It has a role in T cell-dependent B-cell proliferation, differentiation and memory cell formation. Blocking of the CD40-CD40L interaction results in immunoglobulin isotype switch. Defects in CD40L are the cause of X-linked immunodeficiency with hyper-IgM type Ig which is characterized by elavated concentrations of serum IgMs and decreased amou |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD154] |
| Catalog # | MBS584114 |
| Price | $520 |
| Order / More Info | CD154, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nakamura, M et al; Autoantibody to CD40 ligand in systemic lupus erythematosus: association with thrombocytopenia but not thromboembolism. Rheumatology 2006, 45: 150 2. Kissel, K et al; Human platelets target dendritic cell differentiation and production of proinflammatory cytokines. Transfusion 2006, 46: 818 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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