Mouse CD25/IL-2Ra Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD25/IL-2Ra |
| Clone | [7D4] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgM kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Low affinity alpha chain IL-2 receptor (IL-2R alpha), Mr 55 kDa. The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity alpha chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail.^2 CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested.^1, 3, 4 It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220^low TdT^- sIg^- pre-B II and CD45R/B220^low TdT^- sIgM^+sIgD^- immature B cells, but not on the CD45R/B220^low TdT^+ sIg^- pro-B/pre-B I st |
| Immunogen | Immunogen: IL-2-dependent BALB/c mouse helper T-cell clone HT-2 |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673278 |
| Price | $290 |
| Order / More Info | Mouse CD25/IL-2Ra Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Malek, T. R., R. J. Robb, and E. M. Shevach. 1983. Proc. Natl. Acad. Sci. U. S. A. 80:5694.2. Leonard, W.J., et al. 1984. Nature 311:626.3. Ortega, G., R. J. Robb, E. M. Shevach, and T. R. Malek. 1984. J. Immunol. 133:1970.4. Malek, T. R., J. A. Schmidt, and E. M. Shevach. 1985. J. Immunol. 134:2405.5. Rolink, A., U. Grawunder, T.H. Winkler, H. Karasuyama, and F. Melchers. 1994. Int. Immunol. 6:1257.6. Chen, J., A. Ma, F. Young, and F. W. Alt. 1994. International. Immunology 6:1265.7. Habu, S., K. Okumura, T. Diamantstein, and E. M. Shevach. 1985. Eur. J. Immunol. 15:456.8. Moreau, J. L., M. Nabholz, T. Diamantstein, T. R. Malek, E. Shevach, and J. Theze. 1987. Eur. J. Immunol. 17:929.9. Lorenzo, F., C. Jaulin, N. Vita., P. Froussard, P. Ferrara, D. Jankovic, and J. Theze. J. Immunol. 147:2970. |
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MYBIOSOURCE INC.
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