Edit |   |
---|---|
Antigenic Specificity | SNW1 (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SNW1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from human SNW1. Involved in transcriptional regulation. Modulates TGF- beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1- mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate pre |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); SNW domain-containing protein 1; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; Ski-interacting protein; SNW1; SKIIP; SKIP] |
Gene, Accession # | [SNW1], Gene ID: 22938, NCBI: NP_036377.1, UniProt: Q13573 |
Catalog # | MBS9215945 |
Price | $165, $370 |
Order / More Info | SNW1 (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Baudino T.A.,et al.J. Biol. Chem. 273:16434-16441(1998). Dahl R.,et al.Oncogene 16:1579-1586(1998). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Heilig R.,et al.Nature 421:601-607(2003). |