APH1 (N-term), 77-109 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-APH1 (N-term), 77-109 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | APH1 (N-term), 77-109 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This APH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-109 amino acids from the N-terminal region of human APH1. APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. |
| Immunogen | n/a |
| Other Names | [Gamma-secretase subunit APH-1A; APH-1a; Aph-1alpha; Presenilin-stabilization factor; APH1A; PSF] |
| Gene, Accession # | [APH1A], Gene ID: 51107, NCBI: NP_001071096.1, UniProt: Q96BI3 |
| Catalog # | MBS9202592 |
| Price | $165, $370 |
| Order / More Info | APH1 (N-term), 77-109 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ota, T., et al., Nat. Genet. 36(1):40-45 (2004). Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). Marlow, L., et al., Biochem. Biophys. Res. Commun. 305(3):502-509 (2003). Kimberly, W.T., et al., Proc. Natl. Acad. Sci. U.S.A. 100(11):6382-6387 (2003). Edbauer, D., et al., Nat. Cell Biol. 5(5):486-488 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies