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Antigenic Specificity | IL18R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL18R antibody detects endogenous levels of total IL18R. Function: Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (Probable) (PubMed:8626725). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).Subunit Structure: Heterodimer with IL18RAP; within this complex, IL18R1 is involved in ligand-binding and IL18RAP in signaling leading to NF-kappa-B and JNK activation (Probable). Interacts with SLC12A3 in peritoneal macrophages; this interaction is increased by IL18 treatment (By similarity).Similarity: Belongs to the interleukin-1 receptor family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Membrane. Tissue Specificity: Highly expressed in leukocytes, spleen, lung. Also expressed, but at lower levels, in liver, small intestine, colon, prostate, thymus, placenta, and heart. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (80%) |
Other Names | [CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R_HUMAN; IL18R1; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor 1; Interleukin 18 receptor, alpha chain; Interleukin-18 receptor 1] |
Gene, Accession # | [IL18R], Gene ID: 8809, NCBI: NP_001269328.1, UniProt: Q13478 |
Catalog # | MBS9606166 |
Price | $240, $280 |
Order / More Info | IL18R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |