Lambda Light Chain (B-Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLambda Light Chain (B-Cell Marker)
Clone[N10/2]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionThis MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
ImmunogenImmunogen: Purified IgG from human serum Cellular Localization: Cell Surface, Cytoplasmic and secreted
Other Names[Bence Jones Protein; BJP; IGLC 1/2/3; Mcg Marker; Paraprotein]
Gene, Accession #[IGL], Gene ID: 449585; 3535; 3546, NCBI: P01701.2, UniProt: P01701
Catalog #MBS4380045
Price$190, $340, $340
Order / More InfoLambda Light Chain (B-Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLeung N et. al. Leuk Lymphoma doi:10.3109/10428194.2012.673229 (2012). Villaverde et al..Clin Kidney J 5:59-62 (2012).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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