CARD8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCARD8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total CARD8 protein. The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CARD8.
Other Names[CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar]
Gene, Accession #[CARD8], Gene ID: 22900, NCBI: NP_001171829.1, UniProt: Q9Y2G2
Catalog #MBS9409006
Price$255
Order / More InfoCARD8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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