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Antigenic Specificity | Mouse CD11a |
Clone | [mCD11a] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2b |
Format | ion exchange purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |
Immunogen | Immunogen: Enriched mouse peritoneal macrophages. Antibody Properties: Staining and blocking antibody. For staining, use 10 ul/1,000,000 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator. |
Other Names | n/a |
Gene, Accession # | [CD11a] |
Catalog # | MBS140036 |
Price | $305, $455 |
Order / More Info | Mouse CD11a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |