CSN8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CSN8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CSN8 Antibody: The COP9 signalosome (CSN) is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome. The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-comlpexes such as SCF, CSA or DDB2. It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN8 encodes the smallest and the least conserved but first identified subunit of CSN. Recent studies show CSN8 is essential fo |
| Immunogen | Immunogen: CSN8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human CSN8. Buffer: CSN8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [CSN8; COP9; CSN8; SGN8; COP9 signalosome complex subunit 8; COP9 homolog; COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)], [COPS8; COPS8; COP9; CSN8; SGN8; CSN8; SGN8; Signalosome subunit 8; hCOP9] |
| Gene, Accession # | [COPS8], Gene ID: 10920, NCBI: NP_006701, UniProt: Q99627 |
| Catalog # | MBS150159 |
| Price | $375 |
| Order / More Info | CSN8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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