PIWI-L2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIWI-L2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionPIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other
ImmunogenImmunogen: PIWI-L2 antibody was raised against a 14 amino acid synthetic peptide near the center of human PIWI-L2. Buffer: PIWI-L2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PIWI-L2; CT80; HILI; mili; PIWIL1L; Piwi-like protein 2; CT80; piwi-like 2], [PIWIL2; PIWIL2; CT80; HILI; mili; PIWIL1L; HILI; CT80]
Gene, Accession #[PIWIL2], Gene ID: 55124, NCBI: NP_00129193, UniProt: Q8TC59
Catalog #MBS150480
Price$375
Order / More InfoPIWI-L2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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