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Antigenic Specificity | PIWI-L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other |
Immunogen | Immunogen: PIWI-L2 antibody was raised against a 14 amino acid synthetic peptide near the center of human PIWI-L2. Buffer: PIWI-L2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PIWI-L2; CT80; HILI; mili; PIWIL1L; Piwi-like protein 2; CT80; piwi-like 2], [PIWIL2; PIWIL2; CT80; HILI; mili; PIWIL1L; HILI; CT80] |
Gene, Accession # | [PIWIL2], Gene ID: 55124, NCBI: NP_00129193, UniProt: Q8TC59 |
Catalog # | MBS150480 |
Price | $375 |
Order / More Info | PIWI-L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |