Di-Methyl-p53 (K370) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Di-Methyl-p53 (K370) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | n/a |
| Applications | WB, IHC-p, IF, ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclindependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression m |
| Immunogen | Immunogen: Synthesized peptide derived from human p53 around the di-methylation site of K370. Calculated MW: 44kDa Observed MW: 53kDa Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Other Names | [TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53] |
| Gene, Accession # | Gene ID: 7157, UniProt: P04637 |
| Catalog # | MBS2539431 |
| Price | $110, $150, $225 |
| Order / More Info | Di-Methyl-p53 (K370) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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