erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityerbB-2 (Her-2/neu) [4D5-8 (trastuzumab)]
Clonepolyclonal
Host SpeciesHuman
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.2 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
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DescriptionSpecificity: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder. Recombinant monoclonal antibody to erbB-2 (Her-2/neu). Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody 4D5-8 (trastuzumab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
ImmunogenImmunogen: A431 cells (human epidermoid carcinoma) (over)expressing EGFR. Chimeric Use Statement: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
Other Names[Metastatic lymph node gene 19 protein (MLN 19); Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; p185HER2], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19]
Gene, Accession #Gene ID: 2064, UniProt: P04626
Catalog #MBS488049
Price$425
Order / More InfoerbB-2 (Her-2/neu) [4D5-8 (trastuzumab)] Antibody from MYBIOSOURCE INC.
Product Specific ReferencesCarter P, Presta L, Gorman CM, Ridgway JB, Henner D, Wong WL, Rowland AM, Kotts C, Carver ME, Shepard HM. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4285-9. PMID:1350088
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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