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Antigenic Specificity | CBX8 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CBX8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 374-409 amino acids from the C-terminal region of human CBX8. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Immunogen | n/a |
Other Names | [Chromobox protein homolog 8; Polycomb 3 homolog; Pc3; hPc3; Rectachrome 1; CBX8; PC3; RC1] |
Gene, Accession # | [CBX8], Gene ID: 57332, NCBI: NP_065700.1, UniProt: Q9HC52 |
Catalog # | MBS9208445 |
Price | $165, $370 |
Order / More Info | CBX8 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Bardos J.I.,et al.J. Biol. Chem. 275:28785-28792(2000). Michael M.Z.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Garcia-Cuellar M.P.,et al.Oncogene 20:411-419(2001). Levine S.S.,et al.Mol. Cell. Biol. 22:6070-6078(2002). |