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Antigenic Specificity | C5AR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: C5AR1 antibody detects endogenous levels of total C5AR1. Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).Subunit Structure: Homodimer. May also form higher-order |
Immunogen | Immunogen: A synthesized peptide derived from human C5AR1 Subcellular Location: Cell Membrane |
Other Names | [ANAPHYLATOXIN RECEPTOR; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin receptor; C5A; C5a ligand; C5a-R; C5aR; C5AR_HUMAN; c5ar1; C5R1; CD88; CD88 antigen; Complement component 5 receptor 1; Complement component 5 receptor 2; Complement component 5a receptor 1] |
Gene, Accession # | [C5AR1], Gene ID: 728, NCBI: NP_001727.1, UniProt: P21730 |
Catalog # | MBS9603068 |
Price | $240, $280 |
Order / More Info | C5AR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |