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Antigenic Specificity | FRS2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FRS2 |
Other Names | [fibroblast growth factor receptor substrate 2; Fibroblast growth factor receptor substrate 2; fibroblast growth factor receptor substrate 2; fibroblast growth factor receptor substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1] |
Gene, Accession # | [FRS2], Gene ID: 10818, NCBI: NP_001036020.1, UniProt: Q8WU20 |
Catalog # | MBS3223062 |
Price | $335 |
Order / More Info | FRS2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |