Edit |   |
---|---|
Antigenic Specificity | VGFR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This VGFR2 antibody is generated from rabbits immunized with a His fusion protein from human VGFR2. VEGF is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. |
Immunogen | n/a |
Other Names | [Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD309; KDR; FLK1; VEGFR2] |
Gene, Accession # | [KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS9202982 |
Price | $165, $370 |
Order / More Info | VGFR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hong,J.M., et.al., Exp. Mol. Med. (2010) In press Lee,S.J., et.al., Lab. Invest. 90 (3), 374-382 (2010) |