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Antigenic Specificity | Phospho-PI3 Kinase Class III (Ser244/249) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PI3 Kinase Class III (Ser244/249) Antibody detects endogenous levels of PI3 Kinase Class III only when phosphorylated at Ser244/249. Description: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for tra |
Immunogen | Immunogen: A synthesized peptide derived from human PI3 Kinase Class III around the phosphorylation site of Ser244/249. Tissue Specificity: Ubiquitously expressed, with a highest expression in skeletal muscle. |
Other Names | [hVps34; MGC61518; Phosphatidylinositol 3 kinase catalytic subunit type 3; Phosphatidylinositol 3 kinase class 3; Phosphatidylinositol 3 kinase p100 subunit; Phosphatidylinositol 3-kinase catalytic subunit type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide 3 kinase class 3; Phosphoinositide-3-kinase class 3; PI3 kinase type 3; PI3-kinase type 3; PI3K type 3; PK3C3_HUMAN; PtdIns 3 kinase type 3; PtdIns-3-kinase type 3; Vps 34; Vps34] |
Gene, Accession # | [Pik3c3], Gene ID: 5289, NCBI: NP_002638.2, UniProt: Q8NEB9 |
Catalog # | MBS9610783 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PI3 Kinase Class III (Ser244/249) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |