NMDAR2B Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-NMDAR2B antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | NMDAR2B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | N-methyl-D-aspartate receptor (NMDAR) forms a heterodimer of at least one NR1 and one NR2A-D subunit. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits. NR1 subunits bind the co-agonist glycine and NR2 subunits bind the neurotransmitter glutamate. Activation of the NMDA receptor or opening of the ion channel allows flow of Na+ and Ca2+ ions into the cell, and K+ out of the cell (1). Each subunit has a cytoplasmic domain that can be directly modified by the protein kinase/phosphatase (2). PKC can phosphorylate the NR1 subunit (NMDAR1) of the receptor at Ser890/Ser896, and PKA can phosphorylate NR1 at Ser897 |
| Immunogen | Immunogen: A synthetic peptide of human GRIN2B Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [GRIN2B; MGC142178; MGC142180; NMDAR2B; NR2B; hNR3] |
| Gene, Accession # | [NMDAR2B], Gene ID: 2904, NCBI: NP_000825.2, UniProt: Q13224 |
| Catalog # | MBS8501175 |
| Price | $310 |
| Order / More Info | NMDAR2B Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Liu, X.B. et al. (2004) J. Neurosci. 24, 8885-8895. 2. Westphal, R.S. et al. (1999) Science 285, 93-96. 3. Tingley, W.G. et al. (1997) J. Biol. Chem. 272, 5157-5166. 4. Hisatsune, C. et al. (1997) J. Biol. Chem. 272, 20805-20810. 5. Raman, I.M. et al. (1996) Neuron 16, 415-421. 6. Makhinson, M. et al. (1999) J. Neurosci. 19, 2500-2510. 7. Takasu, M.A. et al. (2002) Science 295, 491-495. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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