AGO1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AGO1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: AGO1 antibody detects endogenous levels of total AGO1. Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).Subunit Structure: Interacts with DDB1, DDX5, DDX6, DHX30, DHX36, DDX47, DICER1, AGO2, ELAVL1, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, MOV10, PABPC1, PRMT5, RBM4, SART3, TNRC6B, UPF1 and YBX1. Associates with polysomes and messenger ribonucleoproteins (mNRPs) |
| Immunogen | Immunogen: A synthesized peptide derived from human AGO1 Subcellular Location: Cytoplasm > P-body. Predicted Cross Reactivity: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
| Other Names | [AGO1; AGO1_HUMAN; Argonaute 1; Argonaute1; eIF 2C 1; eIF-2C 1; eIF2C 1; EIF2C; Eif2c1; Eukaryotic translation initiation factor 2C 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; Protein argonaute 1; Protein argonaute-1; Putative RNA binding protein Q99; Putative RNA-binding protein Q99; Q99] |
| Gene, Accession # | [AGO1], Gene ID: 26523, NCBI: NP_001304051.1, UniProt: Q9UL18 |
| Catalog # | MBS9608151 |
| Price | $240, $280 |
| Order / More Info | AGO1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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