BIK Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | BIK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2 (1, 2). Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins (3). Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity (4). |
| Immunogen | Immunogen: Recombinant protein of human BIK Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [BP4; NBK; BIP1] |
| Gene, Accession # | [BIK], Gene ID: 638, NCBI: NP_001188.1, UniProt: Q13323 |
| Catalog # | MBS8500086 |
| Price | $310 |
| Order / More Info | BIK Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Boyd, J. M. et al. (1995) Oncogene 11, 1921-1928. 2. Han, J. et al. (1996) Mol. Cell. Biol. 16, 5857-5864. 3. Tong, Y. et al. (2001) Mol. Cancer Ther. 1, 95-102. 4. Verma, S. et al. (2001) J. Biol. Chem. 276, 4671-4676. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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