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Antigenic Specificity | Mouse Il12b (Center), 196-222 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Il12b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-222 amino acids from the Central region of mouse Il12b. Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity).Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather th |
Immunogen | n/a |
Other Names | [Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; Il12b] |
Gene, Accession # | [Il12b], Gene ID: 16160, NCBI: NP_032378.1, UniProt: P43432 |
Catalog # | MBS9213397 |
Price | $165, $370 |
Order / More Info | Mouse Il12b (Center), 196-222 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kagami, S., et al. J. Immunol. 185(9):5453-5462(2010) Wozniak, T.M., et al. Infect. Immun. 78(10):4187-4194(2010) Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010) Marshall, H.D., et al. J. Immunol. 185(3):1419-1428(2010) Park, Y., et al. J. Immunol. 185(3):1476-1484(2010) |