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Antigenic Specificity | CD146 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with human CD146. The other species are not tested. CD146 belongs to the immunoglobulin super-gene family with five immunoglobulin like domains (V-V-C2-C2-C2), a transmembrane region and a 63 residue cytoplasmic tail. The protein is a membrane glycoprotein that functions as a Ca2+ independent cell adhesion molecule involved in heterophilic cell to cell interactions. CD146 has a molecular size of 130 kDa in its reduced form (118 kDa unreduced), and N linked glycosylation accounts for fifty percent of the apparent molecular weight. In some cells the molecule carries a sulfate 3 glucuronyl moiety. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD146], Gene ID: 4162 |
Catalog # | MBS460041 |
Price | $285 |
Order / More Info | CD146 Antibody from MYBIOSOURCE INC. |
Product Specific References | Johnson, J.P., Rothbacher, U. and Sers, C. The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family. Melanoma Res. 3 (5), 337-340 (1993). |