MRE11 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMRE11
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionMRE11 Antibody: MRE11 is involved in the repair of DNA double strand breaks as part of a complex that includes the Rad50 and NBS1 protein and is thought to act in the same pathway as the A-T mutated (ATM) protein. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for non-homologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. Mutations in this protein result in a novel ataxia telangiectasia-like disorder (
ImmunogenImmunogen: MRE11 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus human MRE11. Buffer: MRE11 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[MRE11; ATLD; HNGS1; MRE11; MRE11B; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; MRE11 meiotic recombination 11 homolog A (S. cerevisiae)], [MRE11A; MRE11A; ATLD; HNGS1; MRE11; MRE11B; HNGS1; MRE11; MRE11 homolog 1; MRE11 homolog A]
Gene, Accession #[MRE11A], Gene ID: 4361, NCBI: EAW66932, UniProt: P49959
Catalog #MBS150224
Price$375
Order / More InfoMRE11 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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