Amyloid-beta (Phospho Thr743) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAmyloid-beta (Phospho Thr743)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA)
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DescriptionSpecificity: Phospho-Amyloid-beta (T743) Polyclonal Antibody detects endogenous levels of Amyloid-beta protein only when phosphorylated at T743. APP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in APP have been implicated in autosomal dominant Alzh
ImmunogenImmunogen: Synthesized peptide derived from human Amyloid-beta around the phosphorylation site of T743
Other Names[Rabbit Amyloid-beta (phospho Thr743); A4; AD1; Amyloid beta A4 protein; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II]
Gene, Accession #[ABPP], Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067
Catalog #MBS9701245
Price$130, $220, $325
Order / More InfoAmyloid-beta (Phospho Thr743) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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