Mouse CD279 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD279 |
| Clone | [RMP1-30] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.25 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse CD279 antibody, clone RMP1-30 recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells. |
| Immunogen | Immunogen: PD-1 transferred BHK cells Fusion Partners: Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; mPD-1; protein PD-1; programmed cell death 1; CD_antigen: CD279], [Pdcd1; Pdcd1; PD-1; Pdc1; Ly101; Pd1; Protein PD-1; mPD-1] |
| Gene, Accession # | [CD279], Gene ID: 18566, NCBI: NP_032824.1, UniProt: Q02242 |
| Catalog # | MBS214319 |
| Price | $430 |
| Order / More Info | Mouse CD279 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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