pan-Shank, 84-309 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | pan-Shank, 84-309 |
| Clone | [S23b-49] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: pan-Shank. This antibody recognizes human, mouse, and rat Shank 1, 2, and 3. Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling. Recent studies suggest that disruption of glutamate receptors at the Shank-postsynaptic platform could contribute to the destruction of postsynaptic density which underlies synaptic dysfunction and loss in Alzheimer's disease. |
| Immunogen | Antigen: Fusion protein corresponding to aa 84-309 (SH3/PDZ domains) of rat Shank2 (accession no. Q9QX74). This sequence is 94% homologous with human and 97% homologous with mouse Shank2. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS190571 |
| Price | $410 |
| Order / More Info | pan-Shank, 84-309 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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