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Antigenic Specificity | KDM1B (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This KDM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 38-73 amino acids from the N-terminal region of human KDM1B. Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri- methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys- 36' of histone H3, |
Immunogen | n/a |
Other Names | [Lysine-specific histone demethylase 1B; 1---; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 2; KDM1B; AOF1; C6orf193; LSD2] |
Gene, Accession # | [KDM1B], Gene ID: 221656, NCBI: NP_694587.3, UniProt: Q8NB78 |
Catalog # | MBS9202155 |
Price | $165, $370 |
Order / More Info | KDM1B (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008). |