KDM1B (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKDM1B (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis KDM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 38-73 amino acids from the N-terminal region of human KDM1B. Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri- methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys- 36' of histone H3,
Immunogenn/a
Other Names[Lysine-specific histone demethylase 1B; 1---; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 2; KDM1B; AOF1; C6orf193; LSD2]
Gene, Accession #[KDM1B], Gene ID: 221656, NCBI: NP_694587.3, UniProt: Q8NB78
Catalog #MBS9202155
Price$165, $370
Order / More InfoKDM1B (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesOta T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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