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Antigenic Specificity | Transferrin receptor protein 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Transferrin receptor protein 1 polyclonal antibody. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
Immunogen | Immunogen: Recombinant Human Transferrin receptor protein 1 protein |
Other Names | [T9; p90; CD71; TFRC] |
Gene, Accession # | Gene ID: 7037, NCBI: NP_001121620.1, UniProt: P02786 |
Catalog # | MBS9416107 |
Price | $320 |
Order / More Info | Transferrin receptor protein 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |