CLSTN1 (N-term), 15-42 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CLSTN1 (N-term), 15-42 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CLSTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human CLSTN1. Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivatio |
| Immunogen | n/a |
| Other Names | [Calsyntenin-1; Alcadein-alpha; Alc-alpha; Alzheimer-related cadherin-like protein; Non-classical cadherin XB31alpha; Soluble Alc-alpha; SAlc-alpha; CTF1-alpha; C-terminal fragment 1-alpha; CLSTN1; CS1; KIAA0911] |
| Gene, Accession # | [CLSTN1], Gene ID: 22883, NCBI: NP_001009566.1, UniProt: O94985 |
| Catalog # | MBS9211964 |
| Price | $165, $370 |
| Order / More Info | CLSTN1 (N-term), 15-42 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Konecna, A., et al. Mol. Biol. Cell 17(8):3651-3663(2006) Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006) Araki, Y., et al. J. Biol. Chem. 279(23):24343-24354(2004) Schmitt-Ulms, G., et al. Nat. Biotechnol. 22(6):724-731(2004) Araki, Y., et al. J. Biol. Chem. 278(49):49448-49458(2003) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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