OPA1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityOPA1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunocytochemistry (ICC), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionOPA1 (optic atrophy protein 1) is a dynamin-related GTPase which forms a diffusion barrier for proteins stored in mitochondrial cristae and is critical to mitochondrial fusion as well as regulation of apoptosis. Intrinsic apoptotic signals mediated proteolytic processing leads OPA1 oligomers disassembly and caspase activator cytochrome C (CYCS) release into mitochondrial intermembrane spaces. Defects in OPA1 are a cause of optic atrophy type 1 (OPA1) as well as dominant optic atrophy plus syndrome (DOA+).
ImmunogenImmunogen: A synthetic peptide made to an internal region within residues 500-600 of human OPA1.
Other Names[dynamin-like 120 kDa protein, mitochondrial isoform 1 preproprotein; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like 120 kDa protein, mitochondrial; OPA1 mitochondrial dynamin like GTPase; Optic atrophy protein 1], [OPA1; OPA1; NPG; NTG; MGM1; BERHS; largeG; MTDPS14; KIAA0567]
Gene, Accession #[OPA1], Gene ID: 4976, NCBI: NP_056375.2, UniProt: O60313
Catalog #MBS555954
Price$490
Order / More InfoOPA1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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