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Antigenic Specificity | Human WNK1 / p65 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, gorilla, human, monkey |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human WNK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. WNK1, a WNK type protein kinase, contains a small N-terminal domain followed by a kinase domain and a long C-terminal tail. The protein is cytoplasmic and has been shown to regulate both the c-Jun N-terminal kinase pathway and the actin cytoskeleton in vitro. WNK1 has been identified as the gene mutant in pseudohypoaldosteronism type 2, also known as Gordon hyperkalemia-hypertension syndrome, which is a rare autosomal dominant form of volume-dependent, low-renin hypertension. |
Immunogen | Immunogen Description: Synthetic 19 amino acid peptide from internal region of human WNK1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Elephant, Panda (95%); Bat, Rabbit, Pig (89%); Mouse, Rat, Hamster (84%). |
Other Names | [WNK1 / p65 (Internal) IHC-plus; WNK1; Erythrocyte 65 kDa protein; HSAN2; KIAA0344; Kinase deficient protein; HWNK1; PHA2C; PRKWNK1; PSK; HSN2; KDP; Human WNK1; p65], [p65] |
Gene, Accession # | [WNK1], Gene ID: 65125, NCBI: NP_061852.2, UniProt: Q9H4A3 |
Catalog # | MBS240875 |
Price | $530 |
Order / More Info | Human WNK1 / p65 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |