SMC6 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SMC6 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC6 |
| Other Names | [structural maintenance of chromosomes protein 6; Structural maintenance of chromosomes protein 6; structural maintenance of chromosomes protein 6; structural maintenance of chromosomes 6] |
| Gene, Accession # | [SMC6], Gene ID: 79677, NCBI: NP_001135758.1, UniProt: Q96SB8 |
| Catalog # | MBS3221676 |
| Price | $335 |
| Order / More Info | SMC6 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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