Human PD-L1 clone 12B4, Tracer Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PD-L1 clone 12B4, Tracer |
| Clone | [12B4] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1,k |
| Format | biotin conjugate |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reactive with human programmed death-ligand 1 (PD-L1). PD-L1, a 40KD transmembrane protein, is a ligand of immune checkpoint protein Programmed Death-1 (PD-1). During T-cell receptor signalling, the binding of PD-L1 to PD-1 transmits an inhibitory signal to activated T-cells to decrease their proliferation. PD-L1 is also believed to play a role in the generation and regulation of Treg cells, and in the enhancement of Treg cell function. PD-L1/PD-1 pathway is important to immune suppression, such as self-tolerance, suppression of immune-rejection during pregnancy and allograft, and immune evasion by cancers. Upregulation of PD-L1 has been found to be associated with many cancer types. For example, increased PD-L1 expression has been shown to |
| Immunogen | Immunogen: Human cell expressed recombinant PDL-1 (Phe19-Arg238) with poly-histidine tag at C-terminus. Light Chain: Kappa. Fusion Myeloma: Sp2/0-Ag14. Target Protein: Human programmed death-ligand 1 (PD-L1), also known as B7H1 or CD274. |
| Other Names | [mAb Human PD-L1; Mouse (mAb) to human programmed death-ligand 1 (PD-L1); mouse mAb to B7H1; mouse mAb to human CD274, Tracer (Biotin Labeled); Biotin conjugated Mouse (mAb) to human programmed death-ligand 1 (PD-L1)], [CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; PD-L12 PublicationsManual assertion based on opinion iniRef.10; PDCD1 ligand 1; Programmed death ligand 1; B7-H11 |
| Gene, Accession # | [PD-L1], Gene ID: 29126, NCBI: NP_001300958.1 |
| Catalog # | MBS590085 |
| Price | $520 |
| Order / More Info | Human PD-L1 clone 12B4, Tracer Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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