GAP43 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGAP43
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesrat, mouse
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentration1mg/ml
ApplicationsImmunofluorescence (IF), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionThe protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ImmunogenImmunogen: GAP43 is very abundant nervous system protein which is found concentrated in neurons. One group discovered it as one of three proteins which becomes unregulated during the regeneration of the toad optic nerve (1). Three GAPs (Growth associated proteins) were discovered, and the number 43 comes from the apparent SDS-PAGE molecular weight of the one named GAP43. The HGNC name for this protein is, not surprisingly, GAP43. Later work showed that GAP43 does not run on SDS-PAGE in a fashion
Other Names[GAP43], [gap43; b-50; pp46]
Gene, Accession #[GAP43], Gene ID: 779658, NCBI: NP_001072212.1
Catalog #MBS415230
Price$370
Order / More InfoGAP43 Antibody from MYBIOSOURCE INC.
Product Specific References1. Skene JH, Willard M. Changes in axonally transported proteins during axon regeneration in toad retinal ganglion cells. J. Cell Biol. 89:86-95 (1981).2. Wiederkehr A, Staple J, Caroni P. The Motility-Associated Proteins GAP-43, MARCKS, and CAP-23 Share Unique Targeting and Surface Activity-Inducing Properties. Exp. Cell Res. 236:103-116 (1997).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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