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Antigenic Specificity | IRF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body. |
Immunogen | Immunogen: A synthesized peptide derived from human IRF1 |
Other Names | [Interferon regulatory factor 1; IRF1; MAR] |
Gene, Accession # | [IRF1], Gene ID: 3659, NCBI: NP_002189.1, UniProt: P10914 |
Catalog # | MBS8542532 |
Price | $280 |
Order / More Info | IRF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |